Publications

Found 43 results
2023
A. Tao, LaCroix, A. S., T. Shoyer, C., Venkatraman, V., Xu, K. L., Feiger, B., and Hoffman, B. D., “Identifying constitutive and context-specific molecular-tension-sensitive protein recruitment within focal adhesions”, Developmental Cell, 2023.
2022
B. D. Andress, Irwin, R. M., Puranam, I., Hoffman, B. D., and McNulty, A. L., “A Tale of Two Loads: Modulation of IL-1 Induced Inflammatory Responses of Meniscal Cells in Two Models of Dynamic Physiologic Loading”, Frontiers in Bioengineering and Biotechnology, vol. 10, 2022.
2021
F. Li, Park, T. Hyun, Sankin, G., Gilchrist, C., Liao, D., Chan, C. U., Mao, Z., Hoffman, B. D., and Zhong, P., “Mechanically induced integrin ligation mediates intracellular calcium signaling with single pulsating cavitation bubbles”, Theranostics, vol. 11, no. 12, pp. 6090 - 6104, 2021.
A. Menaesse, Sumetsky, D., Emanuely, N., Stein, J. L., Gates, E. M., Hoffman, B. D., and Boustany, N. N., “Simplified Instrument Calibration for Wide‐Field Fluorescence Resonance Energy Transfer (FRET) Measured by the Sensitized Emission Method”, Cytometry Part A, vol. 99, no. 4, pp. 407 - 416, 2021.
2020
D. P. Keeley, Hastie, E., Jayadev, R., Kelley, L. C., Chi, Q., Payne, S. G., Jeger, J. L., Hoffman, B. D., and Sherwood, D. R., “Comprehensive Endogenous Tagging of Basement Membrane Components Reveals Dynamic Movement within the Matrix Scaffolding”, Developmental Cell, vol. 54, no. 1, pp. 60 - 74.e7, 2020.
J. - P. Dumas, Jiang, J. Y., Gates, E. M., Hoffman, B. D., Pierce, M. C., and Boustany, N. N., “FRET Efficiency Measurement with a Low-Cost Frequency Domain Fluorescence Lifetime Imaging Microscope”, in Microscopy Histopathology and AnalyticsBiophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN), Washington, DCWashington, D.C., 2020.
A. Menaesse, Sumetsky, D., Emanuely, N., Stein, J. L., Gates, E. M., Hoffman, B. D., and Boustany, N. N., “Simplified Instrument Calibration for Wide‐Field Fluorescence Resonance Energy Transfer (FRET) Measured by the Sensitized Emission Method”, Cytometry Part A, 2020.
2019
S. Sengupta, Rothenberg, K. E., Li, H., Hoffman, B. D., and Bursac, N., “Altering integrin engagement regulates membrane localization of K ir 2.1 channels”, Journal of Cell Science, vol. 132112, no. 17, p. jcs225383, 2019.
J. A. Mosier, Rahman-Zaman, A., Zanotelli, M. R., VanderBurgh, J. A., Bordeleau, F., Hoffman, B. D., and Reinhart-King, C. A., “Extent of Cell Confinement in Microtracks Affects Speed and Results in Differential Matrix Strains”, Biophysical Journal, 2019.
J. - P. Dumas, Jiang, J. Y., Gates, E. M., Hoffman, B. D., Pierce, M. C., and Boustany, N. N., “FRET efficiency measurement in a molecular tension probe with a low-cost frequency-domain fluorescence lifetime imaging microscope”, Journal of Biomedical Optics, vol. 24, no. 12, p. 1, 2019.
T. R. Ham, Collins, K. L., and Hoffman, B. D., “Molecular tension sensors: moving beyond force”, Current Opinion in Biomedical Engineering, vol. 12, pp. 83 - 94, 2019.
C. L. Gilchrist, Leddy, H. A., Kaye, L., Case, N. D., Rothenberg, K. E., Little, D., Liedtke, W., Hoffman, B. D., and Guilak, F., “TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension”, Proceedings of the National Academy of Sciences, vol. 116, pp. 1992–1997, 2019.
2018
D. M. Graham, Andersen, T., Sharek, L., Uzer, G., Rothenberg, K., Hoffman, B. D., Rubin, J., Balland, M., Bear, J. E., and Burridge, K., “Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction”, The Journal of Cell Biology, 2018.
E. M. Gates, LaCroix, A. S., Rothenberg, K. E., and Hoffman, B. D., “Improving Quality, Reproducibility, and Usability of FRET-Based Tension Sensors”, Cytometry Part A, 2018.
K. E. Rothenberg, Puranam, I., and Hoffman, B. D., “Measurement of Force-Sensitive Protein Dynamics in Living Cells Using a Combination of Fluorescent Techniques”, JoVE, no. 141, 2018.
H. Shams, Hoffman, B. D., and Mofrad, M. R. K., “The “Stressful” Life of Cell Adhesion Molecules: On the Mechanosensitivity of Integrin Adhesome”, Journal of Biomechanical Engineering, vol. 140, pp. 020807-020807-7, 2018.
A. S. LaCroix, Lynch, A. D., Berginski, M. E., and Hoffman, B. D., “Tunable molecular tension sensors reveal extension-based control of vinculin loading”, eLife, vol. 7, p. e33927, 2018.
K. E. Rothenberg, Scott, D. W., Christoforou, N., and Hoffman, B. D., “Vinculin Force-Sensitive Dynamics at Focal Adhesions Enable Effective Directed Cell Migration”, Biophysical Journal, vol. 114, pp. 1680 - 1694, 2018.
2017
J. E. Pomeroy, Nguyen, H. X., Hoffman, B. D., and Bursac, N., “Genetically Encoded Photoactuators and Photosensors for Characterization and Manipulation of Pluripotent Stem Cells”, Theranostics, vol. 7, pp. 3539–3558, 2017.
M. Mao, Wang, L., Chang, C. - C., Rothenberg, K. E., Huang, J., Wang, Y., Hoffman, B. D., Liton, P. B., and Yuan, F., “Involvement of a Rac1-Dependent Macropinocytosis Pathway in Plasmid \{DNA\} Delivery by Electrotransfection”, Molecular Therapy, vol. 25, pp. 803 - 815, 2017.
2016
K. L. Collins, Gates, E. M., Gilchrist, C. L., and Hoffman, B. D., “Chapter 1 - Bio-Instructive Cues in Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine”, in Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine, J. L. Brown, Kumbar, S. G., and Banik, B. L., Eds. Academic Press, 2016, pp. 3 - 35.
2015
A. S. LaCroix, Rothenberg, K. E., Berginski, M. E., Urs, A. N., and Hoffman, B. D., “Chapter 10 - Construction, imaging, and analysis of FRET-based tension sensors in living cells”, in Biophysical Methods in Cell Biology, vol. 125, E. K. Paluch, Ed. Academic Press, 2015, pp. 161 - 186.
K. E. Rothenberg, Neibart, S. S., LaCroix, A. S., and Hoffman, B. D., “Controlling Cell Geometry Affects the Spatial Distribution of Load Across Vinculin”, Cellular and Molecular Bioengineering, vol. 8, pp. 364-382, 2015.
A. S. LaCroix, Rothenberg, K. E., and Hoffman, B. D., “Molecular-Scale Tools for Studying Mechanotransduction.”, Annu Rev Biomed Eng, vol. 17, pp. 287-316, 2015.
B. D. Hoffman and Yap, A. S., “Towards a Dynamic Understanding of Cadherin-Based Mechanobiology.”, Trends Cell Biol, vol. 25, no. 12, pp. 803-14, 2015.
2014
B. D. Hoffman, “Chapter One - The Detection and Role of Molecular Tension in Focal Adhesion Dynamics”, in Mechanotransduction, vol. 126, A. J. Engler and Kumar, S., Eds. Academic Press, 2014, pp. 3 - 24.
C. Yan, Liu, D., Li, L., Wempe, M. F., Guin, S., Khanna, M., Meier, J., Hoffman, B., Owens, C., Wysoczynski, C. L., Nitz, M. D., Knabe, W. E., Ahmed, M., Brautigan, D. L., Paschal, B. M., Schwartz, M. A., Jones, D. N. M., Ross, D., Meroueh, S. O., and Theodorescu, D., “Discovery and characterization of small molecules that target the GTPase Ral”, Nature, vol. 515, pp. 443–447, 2014.
K. Moissoglu, Kiessling, V., Wan, C., Hoffman, B. D., Norambuena, A., Tamm, L. K., and Schwartz, M. A., “Regulation of Rac1 translocation and activation by membrane domains and their boundaries”, Journal of Cell Science, vol. 127, pp. 2565-2576, 2014.
P. Y. Hwang, Chen, J., Jing, L., Hoffman, B. D., and Setton, L. A., “The Role Of Extracellular Matrix Elasticity and Composition In Regulating the Nucleus Pulposus Cell Phenotype in the Intervertebral Disc: A Narrative Review”, J Biomech Eng, vol. 136, p. 021010, 2014.
J.  M. Leerberg, Gomez, G.  A., Verma, S., Moussa, E.  J., Wu, S.  K., Priya, R., Hoffman, B.  D., Grashoff, C., Schwartz, M.  A., and Yap, A.  S., “Tension-Sensitive Actin Assembly Supports Contractility at the Epithelial Zonula Adherens”, Current Biology, vol. 24, pp. 1689 - 1699, 2014.
2013
K. Ellis, Hoffman, B. D., and Bagnat, M., “The vacuole within: How cellular organization dictates notochord function”, BioArchitecture, vol. 3, no. 3, pp. 64-68, 2013.
2011
B. D. Hoffman, Grashoff, C., and Grashoff, C., “Dynamic molecular processes mediate cellular mechanotransduction”, Nature, vol. 475, no. 7356, pp. 316-323, 2011.
B. N. Goguen, Hoffman, B. D., Sellers, J. R., Schwartz, M. A., and Imperiali, B., “Light-Triggered Myosin Activation for Probing Dynamic Cellular Processes”, Angewandte Chemie International Edition, vol. 50, pp. 5667–5670, 2011.
2010
S. A. Eucker, Hoffman, B. D., Natesh, R., Ralston, J., Armstead, W. M., and Margulies, S. S., “Development of a fluorescent microsphere technique for rapid histological determination of cerebral blood flow”, Brain Research, vol. 1326, pp. 128 - 134, 2010.
C. Grashoff, Hoffman, B. D., Brenner, M. D., Zhou, R., Parsons, M., Yang, M. T., McLean, M. A., Sligar, S. G., Chen, C. S., Ha, T., and Schwartz, M. A., “Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics”, Nature, vol. 466, no. 7303, 2010.
2009
B. D. Hoffman and Crocker, J. C., “Cell Mechanics: Dissecting the Physical Responses of Cells to Force”, Annual Review of Biomedical Engineering, vol. 11, pp. 259-288, 2009.
2007
B. D. Hoffman, Massiera, G., and Crocker, J. C., “Fragility and mechanosensing in a thermalized cytoskeleton model with forced protein unfolding”, Phys. Rev. E, vol. 76, p. 051906, 2007.
J. C. Crocker and Hoffman, B. D., “Multiple‐Particle Tracking and Two‐Point Microrheology in Cells”, in Cell Mechanics, vol. 83, Y. ‐L. Wang and Discher, D. E., Eds. Academic Press, 2007, pp. 141 - 178.
2006
B. D. Hoffman, Massiera, G., Van Citters, K. M., and Crocker, J. C., “The consensus mechanics of cultured mammalian cells”, Proceedings of the National Academy of Sciences, vol. 103, pp. 10259-10264, 2006.
F. J. Byfield, Hoffman, B. D., Romanenko, V. G., Fang, Y., Crocker, J. C., and Levitan, I., “Evidence for the role of cell stiffness in modulation of volume-regulated anion channels”, Acta Physiologica, vol. 187, pp. 285–294, 2006.
J. Liu, Gardel, M. L., Kroy, K., Frey, E., Hoffman, B. D., Crocker, J. C., Bausch, A. R., and Weitz, D. A., “Microrheology Probes Length Scale Dependent Rheology”, Phys. Rev. Lett., vol. 96, p. 118104, 2006.
K. V. M. Citters, Hoffman, B. D., Massiera, G., and Crocker, J. C., “The Role of F-Actin and Myosin in Epithelial Cell Rheology”, Biophysical Journal, vol. 91, pp. 3946 - 3956, 2006.
2003
A. W. C. Lau, Hoffman, B. D., Davies, A., Crocker, J. C., and Lubensky, T. C., “Microrheology, Stress Fluctuations, and Active Behavior of Living Cells”, Phys. Rev. Lett., vol. 91, p. 198101, 2003.